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Agency officials say they have received reports of problems after patients used versions of semaglutide, the active ingredient in the brand-name medications, that have been compounded or mixed in pharmacies.
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Drug shortages are growing in the United States, and experts see no clear path to resolving them. For patients, that could mean more treatment delays, medication switches and other hassles filling a prescription.
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There's already a huge demand for existing weight-loss drugs, so the new medication is highly anticipated. Obesity affects an estimated 650 million adults globally.
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Online platforms are overflowing with testimonials for GLP-1s. The drugs show promise for inducing weight loss, but many aren’t FDA-approved for that use.
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The Novo Nordisk diabetes medication was found to cause significant weight loss in users and has since become a blockbuster drug and very big business.
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The new weight-loss drugs can be life-changing for people facing health conditions worsened by obesity, but price and spotty insurance coverage may keep them out of reach.