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Becerra faced significant GOP opposition ever since he was nominated, with critics arguing he didn't have sufficient health care experience to run the department.
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The White House says $1,400 checks to many Americans under the bill could begin arriving as soon as this weekend. The bill also directs funding to schools, businesses and vaccine distribution.
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According to the National Conference of State Legislatures, the package includes about $7 billion for cities and counties in Florida.
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Biden moves his timeline up by two months while directing all 50 states and the District of Columbia to move school workers up in line for vaccinations, beginning next week.
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Xavier Becerra, President Biden's nominee for health secretary, faced two hours of questions before a Senate committee on Tuesday.
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The Biden team wants to swiftly vaccinate people of color and others most vulnerable to COVID-19. But health centers are learning that speed and achieving racial equity don't always go hand in hand.
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The cash infusion will go to support the COVAX program, co-run by the World Health Organization, to distribute vaccines to low- and middle-income countries.
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Mayor Rick Kriseman says he backs President Biden’s proposed COVID relief plan because it focuses on his community's physical and economic health.
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It's part of a national initiative to reach underserved communities and starts with 250 centers around the country.
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"We've now purchased enough vaccine supplies to vaccinate all Americans," Biden said on Thursday. "Now we're working to get those vaccines into the arms of millions of people."