genes

About 350 million people suffer from rare diseases, most of which are genetic. But the individual disorders affect relatively few people, so there’s little commercial incentive to bring these treatments to market.

Everybody knows someone — maybe it's you — who got COVID but never got sick or who thinks they never got COVID at all. A new study found one possible reason, involving a certain gene and common colds.

A Mississippi woman's life has been transformed by a treatment for sickle cell disease with the gene-editing technique CRISPR. All her symptoms from a disease once thought incurable have disappeared.

The first brain-delivered gene therapy on the market was recently approved in Europe and the U.K. for a rare genetic disorder called AADC deficiency. It causes developmental delays and movement disorders in kids.

Using CRISPR to modify certain immune cells could make cancer-fighting immunotherapy more potent for a broader set of patients. Two people who went through the treatment share their stories.

The unprecedented study involves using the gene-editing technique CRISPR to edit a gene while it's still inside a patient's body. In exclusive interviews, NPR talks with two of the first participants.

Traditional blood tests still do a better job flagging common inherited diseases. Gene sequencing can be useful for detecting some conditions, but the results can be difficult to interpret.

A congressional committee has upheld a prohibition against the Food and Drug Administration considering using gene-edited embryos to establish pregnancies.

You know your cholesterol, your blood pressure ... your heart gene score? Researchers say a new way of analyzing genetic test data may one day help…

More than a third of patients with cancer of the esophagus responded to experimental treatment in China with the gene-editing technique CRISPR. Several CRISPR studies are underway there.