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Merck Will Help Manufacture Johnson & Johnson's COVID-19 Vaccine

A White House official tells NPR that pharmaceutical giant Merck will help manufacture Johnson & Johnson's COVID-19 vaccine.
Alex Gottschalk
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DeFodi Images via Getty Images
A White House official tells NPR that pharmaceutical giant Merck will help manufacture Johnson & Johnson's COVID-19 vaccine.

Merck traditionally has been a leader in vaccines but has not had success with a COVID-19 vaccine. It's lending a hand to Johnson & Johnson, where production is running significantly behind schedule.

Pharmaceutical giant Merck will help manufacture Johnson & Johnson's COVID-19 vaccine, White House Press Secretary Jen Psaki announced, calling it "an unprecedented historic step," considering that the two companies are normally competitors.

Merck will produce the drug substance at the heart of Johnson & Johnson's vaccine as well as work on filling vaccine vials and getting them ready for distribution.

"The U.S. government will facilitate this partnership in several key ways, including invoking the Defense Production Act to equip two Merck facilities to the standards necessary to safety manufacture the vaccine and asking the Department of Defense to provide daily logistical support to strengthen Johnson & Johnson's efforts," Psaki said during Tuesday afternoon's press briefing.

The Food and Drug Administration authorized Johnson & Johnson's vaccine for emergency use on Saturday, making it the third authorized vaccine against COVID-19 in the U.S. Unlike the other two authorized vaccines, this one requires only one dose and does not need to be kept in ultra-cold freezers, which should make distribution easier.

The White House has said Johnson & Johnson will be able to deliver about 3.9 million doses right away. And Dr. Richard Nettles, vice president of medical affairs for the company's pharmaceutical division, told a congressional subcommittee on Feb. 23 that it will deliver more than 20 million doses by the end of March.

However, according to the schedule in its contract with the federal government, the company is behind. It should be able to deliver 37 million doses by the end of March — not the 20 million Nettles said it can deliver. That may explain why it needs Merck's help.

Johnson & Johnson is under contract to deliver 100 million doses by June.

Merck had been developing its own COVID-19 vaccine candidates, but it announced on Jan. 25 that it was discontinuing the effort following disappointing phase 1 clinical trial results.

Copyright 2021 NPR. To see more, visit https://www.npr.org.

Sydney Lupkin is the pharmaceuticals correspondent for NPR.